Born to a French father and a Sino-Vietnamese mother, Marie-Josephe Jude began studying harp and piano in Nice. On the encouragement of Gyorgy Cziffra, she elected to continue her studies at the Paris Conservatory at the age of 13, where she entered Aldo Ciccolini piano studio and received chamber music instruction from Jean Hubeau. She proved to be a very precocious artist, as she received her diploma (1er prix) in piano performance and a B.Mus. in harp performance from the Ecole Normale de Musique in Paris barely three years later. She was then admitted to the artist's diploma program in Jean-Claude Pennetier's studio.

At the time, Marie-Josephe Jude went regularly to London to study with Maria Curcio-Diamand, disciple of Arthur Schnabel. In 1986, the composer Maurice Ohana opened the doors of contemporary music for her and chose her as his preferred pianist. With this promising debut, Marie-Josephe Jude then went on to be a finalist in the highly prestigious Clara Haskil competition in 1989, and won the "New Talent" award at the Victoires de la Musique in 1995.

Since then, she has played in halls and festivals around the world, from Montpellier to Bath, the Roque d'Antheron to Kuhmo, Bagatelle to Locarno. She has played as a soloist under the batons of J.Märkl, F.Brüggen, C.Dutoit, E.Krivine, F.-X.Roth, J.-Y.Ossonce, J.Axelrod, A.Tamayo, and K.Weise, accompanied by prestigious orchestras such as, in France, the Paris Orchestra, the Nice Philharmonic, the Lyon National Orchestra, Les Siecles, and abroad with orchestras such as the Warsaw Chopin Academy Orchestra, the BBC Scottish Orchestra, the Basel Symphony Orchestra, and the Luxembourg Philharmonic. In December 2009, she was a soloist with the MDR Symphony Orchestra in Leipzig. In February 2011 she was a soloist with the Symphonic Orchestra of Tours (Brahms' Second Piano Concerto).

Chamber music gives her the opportunity to play in more intimate settings. Since 1997, she has been part of a piano duo with Jean-François Heisser, which, however, does not prevent her from playing with other pianists, such as E.Strosser, C.Desert, M.Beroff, and F.Chaplin. String and wind instrument repertoire leads her to collaborate with L.Claret, H.Demarquette, L.Korcia, P.Moragues, X.Phillips, and M.Portal, and lieder allow her to share the stage with M.Delunsch and J.Correas. She also performs regularly as a violin and piano duo with the violinist Jean Marc Phillips-Varjabedian. Lastly, she collaborates regularly on ballets with her brother Charles Jude, principal dancer and director of the Bordeaux ballet.

She is also no stranger to the recording studio. Since 1993, she has been recording the complete Brahms solo piano works (five albums on the Lyrinx label have come out so far). She has also recorded Mendelssohn (Lyrinx, Choc du Monde de la Musique and ffff from Telerama), Jolivet (Lyrinx, Diapason d'Or, and ffff from Telerama), Dutilleux and Ohana (Harmonia Mundi, Choc du Monde de la Musique), among others. She recorded the G. Witkowski quintet (with the Debussy Quartet) in fall 2006, a CD of music by Clara Schumann in January 2008, and more recently an album of Jean Hure's music (Timpani). Her most recent project was an all-Beethoven album released by Lyrinx in 2011.